Our innovations redefine how scientists see the invisible.
The Lew Lab integrates advanced optical design, computation, and biophysical chemistry to create multidimensional optical imaging systems that transcend conventional limits, thereby capturing molecular positions, orientations, chemical environments, and biomolecular interactions in unprecedented detail. The team collaborates across biochemistry, physics, and engineering to translate fundamental discoveries in nanoscale sensing into imaging technologies that accelerate breakthroughs in biology, medicine, and materials science.
We stand up for science.
The Lew Lab is a team of inventors, thinkers, and problem solvers working at the intersection of science and technology.
Creating impactful technology is our passion.
Lab news
Yiyang's and Yuanxin's review, “Single Fluorogens and Orientation-Localization Microscopy for Quantifying Chemical and Biomolecular Dynamics at the Nanoscale”, is now online in Accounts of Chemical Research. Congratulations!
Matt has been promoted to Senior Member of
SPIE. Congratulations!
The group trekked to the
University of Illinois Urbana-Champaign for the 7th Midwest Single Molecule
Workshop. We presented 5 posters, and Matt gave an invited talk.
Our collaborator Emil Gillett and colleagues in the Landes Research Group have published “Fused deep-learning enables 6D single-molecule localization in polarization-resolved microscopy” in Methods and Applications of Fluorescence. Happy reading!
Matt gave an invited talk, “Multidimensional Single-Molecule Imaging: Linking
Rotational Dynamics to Biological Function,” at the Single-Molecule
Approaches to Biology Gordon Research Conference in
Les Diablerets, Switzerland.
Alex received the Professional Development Award from the Department of Electrical and Systems Engineering!
Alex was recognized at the 2026 McKelvey School of
Engineering Engineers' Honors Ceremony. Congratulations, Alex!