We build novel imaging technologies

The Lew Lab builds advanced imaging systems to study biological and chemical systems at the nanoscale. Our technology leverages innovations in applied optics, signal and image processing, design optimization, and physical chemistry. We partner with scientists and engineers across all disciplines to develop technologies to solve unmet needs in science, medicine, and society.
We stand up for science

The Lew Lab is a team of inventors, thinkers, and problem solvers working at the intersection of science and technology.
Creating impactful technology is our passion
Lab news
Congratulations, Brian, on receiving the WashU Imaging Science Pathway
(ISP) Fellowship Award!
Our review, co-authored with Sophie Brasselet, on super-resolution polarization-resolved fluorescence
microscopy is now
online in Nature Photonics. Our lab develops these techniques to create images of molecular 3D
orientations, wobble, and positions. Our advancements open possibilities to explore the nanoscale
organization and conformation of biomolecules as well as to monitor and design local 3D optical fields in
nanophotonics. Read it here:
“Single-molecule orientation and localization
microscopy”
Our correction to “Single-Molecule Orientation Imaging Reveals the Nano-Architecture of Amyloid Fibrils Undergoing Growth and Decay” is now online in Nano Letters.
Matt was a panelist at the Quantum 100
Celebration organized by the Saint Louis Science Center. The
conversation touched on the weirdness of quantum science, how quantum technology touches our everyday lives,
and the exciting future of the field. Thanks to Neville Crenshaw and Ruth Watt at the Science Center for the
invitation!
The Lew Lab welcomes Zhihang Li, an Imaging Science PhD student, and Alex Nie, an undergraduate studying
electrical engineering, to the team!
The Lew Lab welcomed W. E. Moerner, WashU Class of 1975, to campus
during his
50th Reunion
celebration!